The Master’s Program in “Digital Applications and Innovation” of the Department of Informatics of the Ionian University aims to expand the scientific skills of students in modern methodologies and technologies for the utilization of innovative IT applications and in the management of innovation and electronic entrepreneurship. The PMS covers a wide field of knowledge in areas such as big data analytics, mobile computing, tourism and cultural product promotion through modern digital media, biomedicine, robotics, innovation and entrepreneurship in the digital economy, and applications and policies security and privacy on the internet. The PMS lasts one year and it is possible to remotely follow 50% of the theoretical lectures through modern tele-education tools. To obtain the master’s degree, students are expected to prepare an individual empirical research project in which they will apply the methodological tools learned in a practical environment.